What are the common side effects of Octaplasma®?
December 6, 2024
|By WP Admin
A: The common side effects of Octaplasma® include nausea, rash, pruritus, pyrexia and chills; similar to fresh frozen plasma and other blood and blood products.2,19 However, the pooling and immune neutralization, sterile cell filtration,the solvent detergent treatment process and ligand chromatography utilized in manufacturing of Octaplasma® makes it devoid of antibodies implicated in serious adverse events such as transfusion-related acute lung injury pathogenesis,1 reduces risk of pathogen transmission1 and reduces incidence of allergic reactions as compared to fresh frozen plasma.22
In a single- center study comparing Octaplasma® to Cryosupernatant plasma (CSP) for large volume plasma exchange in acute TTP, citrate reactions decreased by >50% and allergic reactions decreased > 60% with use of Octaplasma®.23
Data from the UK between 2012-2021 showed the lowest risk of transfusion reactions for SD Plasma as compared to all other plasma products.24
