Can I use a rapid infuser device to administer Octaplasma®
December 6, 2024
|By WP Admin
According to the approved Canadian product monograph, the Octaplasma® infusion rate must not exceed 1 mL Octaplasma/kg body weight/min or 60 mL Octaplasma/kg/hr. This infusion rate is recommended to avoid the potential risk of citrate toxicity (0.020-0.025 mmol citrate/kg/min) which may result in other health complications.
The recommended rate of infusion rate applies to most patients in receipt of any coagulation active plasma. Most plasma infusions are normally performed with an infusion rate of 10-20 mL/kg/hr, therefore the recommended rate is adequately rapid. If you are using a rapid infuser device, ensure the recommended rate is not exceeded and observe signs of citrate toxicity.
