Are there any differences in the efficacy and safety of Octaplasma® as compared to FFP?
December 6, 2024
|By WP Admin
A: Octaplasma® and FFP do not substantially differ in their clinical efficacy or tolerance.13,14 Studies have reported little difference in the total volume used for plasma exchange between FFP and S/D plasma.15,16,17 In the Netherlands, a 30% decrease in overall plasma utilization was observed post the healthcare system transition to S/D plasma from FFP over 4 years.8
Octaplasma® is associated with reduced risk of pathogen transmission,7 a lower risk of TRALI1 and a lower risk of non-hemolytic transfusion reactions when compared to FFP, particularly allergic reactions and citrate reactions.18,22
