[vc_row unlock_row_content=”yes” row_height_percent=”0″ override_padding=”yes” h_padding=”1″ top_padding=”4″ bottom_padding=”2″ overlay_alpha=”50″ gutter_size=”3″ column_width_percent=”100″ border_color=”color-gyho” shift_y=”0″ z_index=”0″ uncode_shortcode_id=”136534″ border_color_type=”uncode-palette” css=”.vc_custom_1733835801239{border-right-width: 1px !important;}”][vc_column column_width_percent=”100″ gutter_size=”3″ overlay_alpha=”50″ shift_x=”0″ shift_y=”0″ shift_y_down=”0″ z_index=”0″ medium_width=”0″ mobile_width=”0″ width=”1/1″ uncode_shortcode_id=”947959″][vc_custom_heading text_color=”color-xsdn” heading_semantic=”h4″ text_size=”h4″ text_weight=”800″ sub_lead=”yes” sub_reduced=”yes” uncode_shortcode_id=”105450″ subheading=”The use of Octaplasma® in patients undergoing open heart surgery⁶” text_color_type=”uncode-palette” el_class=”single-page-head-bg-color”]Study 1[/vc_custom_heading][vc_row_inner row_inner_height_percent=”0″ force_width_grid=”yes” overlay_alpha=”50″ equal_height=”yes” gutter_size=”3″ border_color=”color-uydo” border_style=”solid” shift_y=”0″ z_index=”0″ uncode_shortcode_id=”197546″ border_color_type=”uncode-palette” limit_content=”” el_class=”inner-page-box-design” css=”.vc_custom_1733827181862{margin-top: 0px !important;}”][vc_column_inner column_width_percent=”100″ gutter_size=”3″ back_color=”color-xsdn” overlay_alpha=”50″ shift_x=”0″ shift_y=”0″ shift_y_down=”0″ z_index=”0″ medium_width=”0″ mobile_width=”0″ width=”1/1″ uncode_shortcode_id=”210108″ back_color_type=”uncode-palette”][vc_custom_heading text_color=”color-742106″ heading_semantic=”h5″ text_size=”h5″ text_weight=”600″ text_transform=”capitalize” separator=”yes” sub_lead=”yes” uncode_shortcode_id=”102189″ text_color_type=”uncode-palette” subheading=”Test whether the tolerability and efficacy of Octaplasma® can compare to FFP in acute surgical situation”]Objectives[/vc_custom_heading][vc_empty_space empty_h=”1″][vc_custom_heading text_color=”color-742106″ heading_semantic=”h5″ text_size=”h5″ text_weight=”600″ text_transform=”capitalize” separator=”yes” sub_lead=”yes” uncode_shortcode_id=”188131″ text_color_type=”uncode-palette” subheading=”Coagulation factors and plasma colloid osmotic pressure”]Evaluation criteria[/vc_custom_heading][vc_empty_space empty_h=”1″][vc_custom_heading text_color=”color-742106″ heading_semantic=”h5″ text_size=”h5″ text_weight=”600″ text_transform=”capitalize” separator=”yes” sub_lead=”yes” uncode_shortcode_id=”135540″ text_color_type=”uncode-palette” subheading=”The choice of Octaplasma® versus FFP did not influence the postoperative course” el_class=”result-card-border”]Results[/vc_custom_heading][vc_empty_space empty_h=”1″][vc_custom_heading text_color=”color-742106″ heading_semantic=”h5″ text_size=”h5″ text_weight=”600″ text_transform=”capitalize” sub_lead=”yes” uncode_shortcode_id=”156425″ text_color_type=”uncode-palette”]Number of patients: 40[/vc_custom_heading][/vc_column_inner][/vc_row_inner][/vc_column][/vc_row][vc_row unlock_row_content=”yes” row_height_percent=”0″ override_padding=”yes” h_padding=”1″ top_padding=”3″ bottom_padding=”2″ overlay_alpha=”50″ gutter_size=”3″ column_width_percent=”100″ border_color=”color-gyho” shift_y=”0″ z_index=”0″ uncode_shortcode_id=”833881″ border_color_type=”uncode-palette” css=”.vc_custom_1733835868818{border-right-width: 1px !important;}”][vc_column column_width_percent=”100″ gutter_size=”3″ overlay_alpha=”50″ shift_x=”0″ shift_y=”0″ shift_y_down=”0″ z_index=”0″ medium_width=”0″ mobile_width=”0″ width=”1/1″ uncode_shortcode_id=”947959″][vc_custom_heading text_color=”color-xsdn” heading_semantic=”h4″ text_size=”h4″ text_weight=”800″ sub_lead=”yes” sub_reduced=”yes” uncode_shortcode_id=”170081″ subheading=”Resuscitation of endotheliopathy and bleeding in thoracic aortic dissections: the VIPER-OCTA randomized clinical pilot trial⁷” text_color_type=”uncode-palette” el_class=”single-page-head-bg-color”]Study 2[/vc_custom_heading][vc_row_inner row_inner_height_percent=”0″ force_width_grid=”yes” overlay_alpha=”50″ equal_height=”yes” gutter_size=”3″ border_color=”color-uydo” border_style=”solid” shift_y=”0″ z_index=”0″ uncode_shortcode_id=”197546″ border_color_type=”uncode-palette” limit_content=”” el_class=”inner-page-box-design” css=”.vc_custom_1733827181862{margin-top: 0px !important;}”][vc_column_inner column_width_percent=”100″ gutter_size=”3″ back_color=”color-xsdn” overlay_alpha=”50″ shift_x=”0″ shift_y=”0″ shift_y_down=”0″ z_index=”0″ medium_width=”0″ mobile_width=”0″ width=”1/1″ uncode_shortcode_id=”210108″ back_color_type=”uncode-palette”][vc_custom_heading text_color=”color-742106″ heading_semantic=”h5″ text_size=”h5″ text_weight=”600″ text_transform=”capitalize” separator=”yes” sub_lead=”yes” uncode_shortcode_id=”754370″ text_color_type=”uncode-palette” subheading=”Compare the effect of coagulation support with S/D-treated pooled plasma (Octaplasma®) versus standard FFP”]Objectives[/vc_custom_heading][vc_empty_space empty_h=”0″][vc_custom_heading text_color=”color-742106″ heading_semantic=”h5″ text_size=”h5″ text_weight=”600″ text_transform=”capitalize” separator=”yes” sub_lead=”yes” uncode_shortcode_id=”118852″ text_color_type=”uncode-palette” subheading=”Glycocalyx and endothelial injury, bleeding, and transfusion requirements”]Evaluation criteria[/vc_custom_heading][vc_empty_space empty_h=”0″][vc_custom_heading text_color=”color-742106″ heading_semantic=”h5″ text_size=”h5″ text_weight=”600″ text_transform=”capitalize” separator=”yes” sub_lead=”yes” uncode_shortcode_id=”133113″ text_color_type=”uncode-palette” subheading=”Octaplasma® reduced glycocalyx and endothelial injury, reduced bleeding, transfusions, use of prohemostatics, and time on ventilator after surgery compared to standard FFP” el_class=”result-card-border”]Results[/vc_custom_heading][vc_empty_space empty_h=”0″][vc_custom_heading text_color=”color-742106″ heading_semantic=”h5″ text_size=”h5″ text_weight=”600″ text_transform=”capitalize” sub_lead=”yes” uncode_shortcode_id=”106830″ text_color_type=”uncode-palette”]Number of patients: 44[/vc_custom_heading][/vc_column_inner][/vc_row_inner][vc_raw_html]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[/vc_raw_html][/vc_column][/vc_row][vc_row][vc_column width=”1/1″][vc_column_text text_lead=”small” uncode_shortcode_id=”763450″]Adapted from the Octaplasma® Product Monograph, Solheim et al, and Stensballe et al.[/vc_column_text][/vc_column][/vc_row][vc_row][vc_column width=”1/1″][uncode_block id=”119746″][/vc_column][/vc_row][vc_row][vc_column width=”1/1″][/vc_column][/vc_row]